The shortened 2020 baseball season was followed by a shorter postseason for the Minnesota Twins. The Twins were swept two games to none in the Wild Card Round of the MLB Playoffs by the Houston Astros. The Astros won Game 1 by a score of 4-1 and Game 2 by a score of 3-1.

For this Twins, they added to a record they hold; longest playoff losing streak in baseball history. The Twins have now lost 18 consecutive postseason games. Their last win was October 5, 2004 in Game 1 of the ALDS versus the New York Yankees.